| 產(chǎn)品編號(hào) | bs-21296R-AP |
| 英文名稱 | Rabbit Anti-RBM42/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的RNA結(jié)合蛋白42抗體 |
| 別 名 | MGC10433; RNA binding motif protein 42; RNA binding protein 42. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 結(jié)合蛋白 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 50kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RBM42 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: RNA binding motif protein 42 (RBM42) C-terminal domain interacts with HNRNPK C-terminla domain and RNA. RBM42 and HNRNPK are involved in the maintenance of cellular ATP levels during stress, possibly by protecting critical mRNAs. Upon stress response, RBM42 localizes with HNRNPK in cytoplasmic aggregates of stalled translational pre-initiation complexes called stress granules. There are 4 isoforms produced by alternative splicing. Function: Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA. Subunit: Interacts with HNRNPK. Subcellular Location: Cytoplasmic and Nuclear. Similarity: Belongs to the RRM RBM42 family. Contains 1 RRM (RNA recognition motif) domain. Database links: Entrez Gene: 79171 Human Entrez Gene: 68035 Mouse GenBank: NP_077297.2 Human Omim: 613232 Human SwissProt: Q9BTD8 Human SwissProt: Q91V81 Mouse Unigene: 5086 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
