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Rabbit Anti-RBM17/AP Conjugated antibody (bs-19765R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-19765R-AP
英文名稱 Rabbit Anti-RBM17/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的RNA結(jié)合蛋白17抗體
別    名 45 kDa-splicing factor; RBM 17; Rbm17; RNA binding motif protein 17; RNA binding motif protein17; RNA-binding motif protein 17; SPF 45; SPF45; SPF45_HUMAN; Splicing factor (45 kD); Splicing factor (45kD); Splicing factor 45; Splicing factor 45 kDa; Splicing factor 45kDa.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human RBM17
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes an RNA binding protein. The encoded protein is part of the spliceosome complex and functions in the second catalytic step of mRNA splicing. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 9 and 15. [provided by RefSeq, Mar 2009]

Function:
Splice factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites. Promotes the utilization of a cryptic splice site created by the beta-110 mutation in the HBB gene. The resulting frameshift leads to sickle cell anemia.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 G-patch domain.
Contains 1 RRM (RNA recognition motif) domain.

Database links:

Entrez Gene: 84991 Human

Entrez Gene: 76938 Mouse

Entrez Gene: 291295 Rat

Omim: 606935 Human

SwissProt: Q96I25 Human

SwissProt: Q8JZX4 Mouse

Unigene: 498548 Human

Unigene: 182769 Mouse

Unigene: 20694 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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