| 產(chǎn)品編號(hào) | bs-19832R-BF488 |
| 英文名稱 | Rabbit Anti-SLC39A4/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的溶質(zhì)載體家族蛋白39成員A4抗體 |
| 別 名 | 1600025H15Rik; Acrodermatitis enteropathica zinc deficiency type; Activated in W/Wv mouse stomach 2; AEZ; AU041686; AWMS2; FLJ20327; MGC156705; MGC74741; S39A4_HUMAN; Slc39a4; Solute carrier family 39 member 4; Ssolute carrier family 39 zinc transporter member 4; Zinc transporter ZIP4; ZIP-4; ZIP4; Zrt and Irt like protein 4; Zrt- and Irt-like protein 4. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)運(yùn)蛋白 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 66kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human SLC39A4 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] Function: Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability. Subcellular Location: Cell membrane. Recycling endosome membrane. Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability. Tissue Specificity: Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum. DISEASE: Acrodermatitis enteropathica, zinc-deficiency type (AEZ) Similarity: Belongs to the ZIP transporter (TC 2.A.5) family. Database links: Entrez Gene: 55630 Human Entrez Gene: 72027 Mouse Omim: 607059 Human SwissProt: Q6P5W5 Human SwissProt: Q78IQ7 Mouse Unigene: 521934 Human Unigene: 276829 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
