產(chǎn)品編號 |
bs-10742R-RBITC |
英文名稱 |
Rabbit Anti-LPCAT2/RBITC Conjugated antibody
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中文名稱 |
羅丹明(RBITC)標(biāo)記的磷脂?;D(zhuǎn)移酶2抗體 |
別 名 |
1 acylglycerophosphocholine O acyltransferase; 1 alkylglycerophosphocholine O acetyltransferase; 1-acylglycerophosphocholine O-acyltransferase; 1-alkylglycerophosphocholine O-acetyltransferase; A330042H22; Acetyl CoA:lyso PAF acetyltransferase; Acetyl-CoA:lyso-PAF acetyltransferase; Acetyl-CoA:lyso-platelet-activating factor acetyltransferase; acyl CoA:lysophosphatidylcholine acyltransferase 2; Acyl-CoA:lysophosphatidylcholine acyltransferase member 1; Acyltransferase like 1A; Acyltransferase-like 1; AYTL1; Aytl1a; DKFZp686H22112; FLJ20481; lpafat1; LPC acyltransferase 2; LPCAT-2; LPCAT2; Lyso PAF acetyltransferase; Lyso platelet activating factor (PAF) acetyltransferase; Lyso-PAF acetyltransferase; LysoPAFAT; LysoPAFAT/LPCAT2; LysoPC acyltransferase 2; Lysophosphatidylcholine acyltransferase 2; OTTMUSP00000029641; PCAT2_HUMAN; RGD1563994. |
規(guī)格價格 |
100ul/2980元
購買 大包裝/詢價 |
說 明 書 |
100ul
|
研究領(lǐng)域 |
細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 轉(zhuǎn)運蛋白 |
抗體來源 |
Rabbit |
克隆類型 |
Polyclonal |
交叉反應(yīng) |
Human, Mouse, Rat,
(predicted: Pig, Cow, Horse, Rabbit, Sheep, )
|
產(chǎn)品應(yīng)用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
分 子 量 |
60kDa |
性 狀 |
Lyophilized or Liquid |
濃 度 |
1mg/ml |
免 疫 原 |
KLH conjugated synthetic peptide derived from human LPCAT2 |
亞 型 |
IgG |
純化方法 |
affinity purified by Protein A |
儲 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
產(chǎn)品介紹 |
background: This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009].
Function: Possesses both acyltransferase and acetyltransferase activities. Activity is calcium-dependent. Involved in platelet-activating factor (PAF) biosynthesis by catalyzing the conversion of the PAF precursor, 1-O-alkyl-sn-glycero-3-phosphocholine (lyso-PAF) into 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine (PAF). Also converts lyso-PAF to 1-alkyl-phosphatidylcholine (PC), a major component of cell membranes and a PAF precursor. Under resting conditions, acyltransferase activity is preferred. Upon acute inflammatory stimulus, acetyltransferase activity is enhanced and PAF synthesis increases.
Subcellular Location: Endoplasmic reticulum membrane. Golgi apparatus membrane.
Similarity: Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
Contains 2 EF-hand domains.
Database links:
Entrez Gene: 54947 Human
Omim: 612040 Human
SwissProt: Q7L5N7 Human
Unigene: 460857 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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