| 產(chǎn)品編號(hào) |
bs-14324R-PE-Cy5.5 |
| 英文名稱 |
Rabbit Anti-DHX8/PE-Cy5.5 Conjugated antibody
|
| 中文名稱 |
PE-Cy5.5標(biāo)記的DHX8蛋白抗體 |
| 別 名 |
ATP dependent RNA helicase DHX8;
ATP-dependent RNA helicase dhx8;
DDX 8;
DDX8;
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8 (RNA helicase);
DEAD/H (Asp Glu Ala Asp/His) box polypeptide 8;
DEAD/H box polypeptide 8;
DEAH (Asp Glu Ala His) box polypeptide 8;
DEAH box polypeptide 8;
DEAH box protein 8;
DHX 8;
dhx8;
DHX8_HUMAN;
HRH 1;
HRH1;
PRP 22;
PRP22;
PRPF 22;
PRPF22;
RNA helicase HRH 1;
RNA helicase HRH1. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買 大包裝/詢價(jià) |
| 說 明 書 |
100ul
|
| 研究領(lǐng)域 |
細(xì)胞生物 細(xì)胞分化 表觀遺傳學(xué) |
| 抗體來源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
(predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
|
| 產(chǎn)品應(yīng)用 |
ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
139kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human DHX8 |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is highly homologous to yeast Prp22. This protein facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome. [provided by RefSeq, Jul 2008]
Function:
Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Subunit:
Identified in the spliceosome C complex. Interacts with ARRB2; the interaction is detected in the nucleus upon OR1D2 stimulation.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the DEAD box helicase family. DEAH subfamily. DDX8/PRP22 sub-subfamily.
Contains 1 helicase ATP-binding domain.
Contains 1 helicase C-terminal domain.
Contains 1 S1 motif domain.
Database links:
Entrez Gene: 1659 Human
Entrez Gene: 217207 Mouse
Entrez Gene: 287727 Rat
Omim: 600396 Human
SwissProt: Q14562 Human
SwissProt: A2A4P0 Mouse
Unigene: 463105 Human
Unigene: 28186 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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