日日操日日操,亚洲一区二区三区四区视频,成人午夜福利激情,无码中文7幕

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
人妻交换久久,www.av天天天天天天,刘玥欧美精品
Rabbit Anti-ING4/Cy5.5 Conjugated antibody (bs-10492R-Cy5.5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-10492R-Cy5.5
英文名稱 Rabbit Anti-ING4/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標(biāo)記的ING4抗體
別    名 Brain my036 protein; Candidate tumor suppressor p33 ING 1 homolog; Candidate tumor suppressor p33 ING-1 homolog; Candidate tumor suppressor p33 ING1 homolog; D6Wsu147e; D6Xrf92; ING 1 like protein; ING 4; ING-1 like protein; ING-4; ING1 like protein; ING4; ING4_HUMAN; Inhibitor of growth family member 4; Inhibitor of growth family member 4 long isoform; Inhibitor of growth protein 4; MGC12557; my036; p29 ING 4; p29 ING-4; p29 ING4; p29ING4; My036; inhibitor of growth protein 4 isoform 1.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  發(fā)育生物學(xué)  染色質(zhì)和核信號(hào)  轉(zhuǎn)錄調(diào)節(jié)因子  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 27kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ING4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins. [provided by RefSeq, Jul 2008].

Function:
Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo. Through chromatin acetylation it may function in DNA replication. May inhibit tumor progression by modulating the transcriptional output of signaling pathways which regulate cell proliferation. Can suppress brain tumor angiogenesis through transcriptional repression of RELA/NFKB3 target genes when complexed with RELA. May also specifically suppress loss of contact inhibition elicited by activated oncogenes such as MYC. Represses hypoxia inducible factor's (HIF) activity by interacting with HIF prolyl hydroxylase 2 (EGLN1).

Subunit:
Homodimer. Interacts with H3K4me3 and to a lesser extent with H3K4me2, the interaction augments HBO1 acetylation activity on H3 tails. Component of the HBO1 complex composed at least of ING4 or ING5, KAT7/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17. Interacts with EP300, RELA and TP53; these interactions may be indirect. Interacts with EGLN1.

Subcellular Location:
Nucleus.

Post-translational modifications:
Citrullination by PADI4 within the nuclear localization signal disrupts the interaction with p53 and increases susceptibility to degradation.

Similarity:
Belongs to the ING family.
Contains 1 PHD-type zinc finger.

Database links:
UniProtKB/Swiss-Prot: Q9UNL4 human
UniProtKB/Swiss-Prot: Q8C0D7 mouse

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.bklrv.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
亚洲一区二区三区枫花恋| av在线b b b| 国产老熟女精品| 91精品国产91久久久久久吃药 | 亚洲,欧洲,日韩一区,二区| 亚洲另类一二区| 99久久综合精品国产首员无码| 一级黄片AV在线| 91Chinese高清无码| 日韩欧乱伦故事| 欧美成在线一级a| ai换脸av在线| 人妻熟女一区二区在线AⅤ| 香蕉中文在线w片播放| 亚洲男人的av天堂| 婷婷五月天激情欧美基地| 日韩无码干干干| 色呦呦18禁| 97在线午夜福| 麻豆一区二区视频免费看| 成人永久性视频| 久久婷婷精品婷婷| 国产91青青操| 一区二区三区国产欧美吃瓜| 国产伦理片午夜福利| 少妇高潮久久久久久久久000| 欧美一区二区三区午夜精品| 色呦呦精品一区二区| 天堂a在线地址22最新版| 欧美日韩在线视频免费观看一级| 亚洲永久中文字幕| 十八禁视频福利| 免费黄色点级片| 亚洲国产精品欧美在线观看| 成人免费视频手机版| 久久久无码国产精品一区| 久久久久久88区| 在线观看精品福利| 欧美亚洲综合美| 蜜臀av一区二区三区多| 精品孕妇一区二区三区|