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Rabbit Anti-ZBED3/BF488 Conjugated antibody (bs-13553R-BF488)
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說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13553R-BF488
英文名稱 Rabbit Anti-ZBED3/BF488 Conjugated antibody
中文名稱 BF488標(biāo)記的鋅指蛋白BED3抗體
別    名 MGC15435; ZBED3; ZBED3_HUMAN; Zinc finger BED domain containing 3; Zinc finger BED domain-containing protein 3; Zinc finger BED type containing 3.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  鋅指蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 25kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ZBED3
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Acts as a positive regulator in the activation of the canonical Wnt/beta-catenin signaling pathway by stabilizing cytoplasmic beta-catenin. Involved in transcription activation of Wnt target gene expression.

Subunit:
Interacts with AXIN1; the interaction is direct, enhanced by protein kinase GSK3B and casein kinase CSNK1E activities and decreases GSK3B-induced beta-catenin serine and threonine phosphorylations.

Subcellular Location:
Cytoplasm. Membrane. Note=Colocalizes with AXIN1 in the cytoplasm.

Similarity:
Contains 1 BED-type zinc finger.

Database links:

Entrez Gene: 84327 Human

Entrez Gene: 72114 Mouse

Entrez Gene: 361881 Rat

SwissProt: Q96IU2 Human

Unigene: 584988 Human

Unigene: 3774 Mouse

Unigene: 103511 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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