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Rabbit Anti-DGKK/PE-Cy7 Conjugated antibody (bs-14300R-PE-Cy7)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-14300R-PE-Cy7
英文名稱 Rabbit Anti-DGKK/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標(biāo)記的甘油二酯激酶κ/DGK-κ抗體
別    名 142 kDa diacylglycerol kinase; DAG kinase kappa; DGK kappa; DGKK_HUMAN; Diacylglycerol kinase kappa; Diglyceride kinase kappa.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  新陳代謝  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 142kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DGKK
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011]

Function:
DGKK (Diacylglycerol kinase kappa) phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA).

Subunit:
Does not form homooligomers.

Subcellular Location:
Cytoplasm. Membrane; Peripheral membrane protein

Tissue Specificity:
Expressed in testis, and to a lesser extent in placenta.

Post-translational modifications:
Phosphorylated at Tyr-78 by some member of the SRC family in response to H(2)O(2).

Similarity:
Belongs to the eukaryotic diacylglycerol kinase family.
Contains 1 DAGKc domain.
Contains 1 PH domain.
Contains 2 phorbol-ester/DAG-type zinc fingers.

Database links:

Entrez Gene: 139189 Human

Entrez Gene: 331374 Mouse

SwissProt: Q5KSL6 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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