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Rabbit Anti-SOX1/BF555 Conjugated antibody (bs-12276R-BF555)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12276R-BF555
英文名稱 Rabbit Anti-SOX1/BF555 Conjugated antibody
中文名稱 BF555標記的核轉(zhuǎn)錄因子抗體
別    名 sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SOX-1; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 發(fā)育生物學(xué)  神經(jīng)生物學(xué)  干細胞  轉(zhuǎn)錄調(diào)節(jié)因子  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Pig, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 39kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human SOX6
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.

Function:
Transcriptional activator.

Subcellular Location:
Nucleus.

Tissue Specificity:
Mainly expressed in the developing central nervous system.

Post-translational modifications:
Sumoylation inhibits the transcriptional activity.

Similarity:
Contains 1 HMG box DNA-binding domain.

Database links:

Entrez Gene: 6656 Human

Entrez Gene: 20664 Mouse

Omim: 602148 Human

SwissProt: O00570 Human

SwissProt: P53783 Mouse

Unigene: 202526 Human

Unigene: 39088 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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