| 產(chǎn)品編號 | bs-12276R-RBITC |
| 英文名稱 | Rabbit Anti-SOX1/RBITC Conjugated antibody |
| 中文名稱 | 羅丹明（RBITC）標(biāo)記的核轉(zhuǎn)錄因子抗體 |
| 別 名 | sex determining region Y box 1; sox1; SOX1_HUMAN; SRY; SOX-1; SRY box containing gene 1; SRY related HMG box gene 1; Transcription factor Sox-1. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 發(fā)育生物學(xué) 神經(jīng)生物學(xué) 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Pig, ) |
| 產(chǎn)品應(yīng)用 | ICC=1:50-200 IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 39kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from Human SOX6 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal. Function: Transcriptional activator. Subcellular Location: Nucleus. Tissue Specificity: Mainly expressed in the developing central nervous system. Post-translational modifications: Sumoylation inhibits the transcriptional activity. Similarity: Contains 1 HMG box DNA-binding domain. Database links: Entrez Gene: 6656 Human Entrez Gene: 20664 Mouse Omim: 602148 Human SwissProt: O00570 Human SwissProt: P53783 Mouse Unigene: 202526 Human Unigene: 39088 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
