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Rabbit Anti-CPEB2/BF488 Conjugated antibody (bs-14019R-BF488)
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說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-14019R-BF488
英文名稱(chēng) Rabbit Anti-CPEB2/BF488 Conjugated antibody
中文名稱(chēng) BF488標(biāo)記的細(xì)胞質(zhì)多聚腺苷酸結(jié)合蛋白2抗體
別    名 CPE binding protein 2; CPE BP2; CPEB 2; CPEBP2; Cytoplasmic polyadenylation element binding protein 2; hCPEB 2; hCPEB2; CPEB2_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 65kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CPEB2
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The protein encoded by this gene is highly similar to cytoplasmic polyadenylation element binding protein (CPEB), an mRNA-binding protein that regulates cytoplasmic polyadenylation of mRNA as a trans factor in oogenesis and spermatogenesis. Studies of the similar gene in mice suggested a possible role of this protein in transcriptionally inactive haploid spermatids. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Function:
CPEB2, (Cytoplasmic polyadenylation element-binding protein 2), belongs to the RRM CPEB family and contains 2 RRM (RNA recognition motif) domains. It may bind poly(U) RNA oligomers. It may play a role in translational regulation of stored mRNAs in transcriptionally inactive haploid spermatids. There are 7 named isoforms [FASTA] produced by alternative splicing.

Subcellular Location:
Cytoplasmic

Similarity:
Belongs to the RRM CPEB family.
Contains 2 RRM (RNA recognition motif) domains.

Database links:

Entrez Gene: 132864 Human

Entrez Gene: 231207 Mouse

Entrez Gene: 360949 Rat

Omim: 610605 Human

SwissProt: Q7Z5Q1 Human

SwissProt: Q812E0 Mouse

Unigene: 656937 Human

Unigene: 162283 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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