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Rabbit Anti-JAKMIP1/GABABRBP/Gold Conjugated antibody (bs-12086R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-12086R-Gold
英文名稱 Rabbit Anti-JAKMIP1/GABABRBP/Gold Conjugated antibody
中文名稱 膠體金標記的G氨基丁酸B型受體結合蛋白抗體
別    名 FLJ31564; GABA B receptor binding protein; GABA-B receptor-binding protein; GABABRBP; Jak and microtubule interacting protein 1; JAKMIP 1; JAKMIP1; JAMIP1; Janus kinase and microtubule interacting protein 1; Janus kinase and microtubule-interacting protein 1; JKIP1_HUMAN; Marlin 1; Marlin-1; MARLIN1; Multiple alpha-helices and RNA-linker protein 1; Multiple coiled coil GABABR1 binding protein.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  神經生物學  信號轉導  激酶和磷酸酶  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 73kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GABABRBP/JAKMIP1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.

Function:
Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.

Subunit:
Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2.

Subcellular Location:
Cytoplasm > cytoskeleton. Membrane. Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.

Tissue Specificity:
Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.

Similarity:
Belongs to the JAKMIP family.

Database links:

Entrez Gene: 152789 Human

Entrez Gene: 76071 Mouse

Entrez Gene: 305434 Rat

Omim: 611195 Human

SwissProt: Q96N16 Human

SwissProt: Q8BVL9 Mouse

SwissProt: Q3SWS9 Rat

Unigene: 479066 Human

Unigene: 85280 Mouse

Unigene: 18970 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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