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Rabbit Anti-PIBF/AP Conjugated antibody (bs-0420R-AP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0420R-AP
英文名稱 Rabbit Anti-PIBF/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的孕激素誘導阻斷因子抗體
別    名 progesterone induced blocking factor; KIAA1008; PIBF 1; PIBF; PIBF1; Progesterone immunomodulatory binding factor 1; Progesterone induced blocking factor 1; PIBF1_HUMAN; RP11 505F3.1; CEP90; C13orf24; RP11-505F3.1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 免疫學  細胞周期蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 83kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PIBF
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
C13orf24 is also known as Progesterone-induced-blocking factor 1 (PIBF1). PIBF1 is synthesized by lymphocytes of healthy pregnant women in the presence of progesterone and inhibits arachidonic acid release, by acting on the phospholipase A2 enzyme, inducing a Th2 biased immune response. It also controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect.

Function:
Mediator of progesterone that by acting on the phospholipase A2 enzyme interferes with arachidonic acid metabolism, induces a Th2 biased immune response, and by controlling NK activity exerts an anti-abortive effect.

Tissue Specificity:
Expressed at highest levels in testis. Moderate expression is detected in spleen, thymus, prostate, ovary, small intestine, and colon.

Database links:

Entrez Gene: 10464 Human

Entrez Gene: 52023 Mouse

Entrez Gene: 306104 Rat

Omim: 607532 Human

SwissProt: Q8WXW3 Human

Unigene: 441926 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

孕激素誘導阻斷因子又稱孕酮誘導的封閉因子性蛋白。
妊娠期間淋巴細胞生成孕酮受體且釋放一種稱之為孕酮誘導的封閉因子性蛋白(PIBF),PIBF有很強的抗NK細胞活性,PIBF陽性淋巴細胞分泌IL-10。
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