| 產(chǎn)品編號(hào) | bs-6413R-APC |
| 英文名稱 | Rabbit Anti-Tetranectin/APC Conjugated antibody |
| 中文名稱 | APC標(biāo)記的四連接素TN抗體 |
| 別 名 | C type lectin domain family 3 member B; C-type lectin domain family 3 member B; Clec3b; Plasminogen kringle 4 binding protein; Plasminogen kringle 4-binding protein; TETN_HUMAN; Tetranectin; TN; TNA. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 細(xì)胞骨架 細(xì)胞外基質(zhì) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 22, 80kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Tetranectin/CLEC3B/TNA |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Function: Tetranectin binds to plasminogen and to isolated kringle 4. May be involved in the packaging of molecules destined for exocytosis. Subunit: Homotrimer. Subcellular Location: Secreted. Tissue Specificity: Found in plasma. Similarity: Contains 1 C-type lectin domain. Database links: UniProtKB/Swiss-Prot: P05452.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 四連接素(Tetranectin， TN)是一種血纖維蛋白溶酶原結(jié)合蛋白，可出現(xiàn)在血漿及細(xì)胞外基質(zhì)(extracellular matrix， ECM)。TN除了它的血纖維蛋白溶酶原結(jié)合蛋白特性外，還能與肝磷脂、載脂蛋白(a)，組織纖維蛋白溶酶原激活劑，肝細(xì)胞生長(zhǎng)因子及血管他丁。TN的表達(dá)可在各種內(nèi)分泌組織、內(nèi)皮細(xì)胞、及間質(zhì)細(xì)胞檢測(cè)到，其中間質(zhì)細(xì)胞包括成纖維細(xì)胞、單核細(xì)胞和中性粒細(xì)胞。血清TN水平的下降可見(jiàn)于創(chuàng)傷后或急性心肌梗塞后，類風(fēng)濕性關(guān)節(jié)炎及惡性腫瘤等。雖然TN的確切生物學(xué)功能未被證實(shí)，一些實(shí)驗(yàn)證據(jù)表明TN在組織的修復(fù)重建中起重要的作用。TN可以增加組織型纖維蛋白溶酶原激活劑催化激活纖維蛋白溶酶原以多聚賴氨酸的催化激活作用。因?yàn)榛罨睦w維蛋白溶酶原被公認(rèn)在細(xì)胞外基質(zhì)的退變中起重要作用。 |
