| 產(chǎn)品編號(hào) |
bs-0098R-Cy3 |
| 英文名稱 |
Rabbit Anti-GIP/Cy3 Conjugated antibody
|
| 中文名稱 |
Cy3標(biāo)記的胃泌素抑制肽抗體 |
| 別 名 |
Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic polypeptide; Incretin hormone. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買(mǎi) 大包裝/詢價(jià) |
| 說(shuō) 明 書(shū) |
100ul
|
| 研究領(lǐng)域 |
信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素 轉(zhuǎn)錄調(diào)節(jié)因子 糖尿病 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類型 |
Polyclonal |
| 交叉反應(yīng) |
Mouse,
(predicted: Human, Rat, Pig, Cow, )
|
| 產(chǎn)品應(yīng)用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
5/17kDakDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human GIP |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion.
Function:
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.
Subcellular Location:
Secreted.
Similarity:
Belongs to the glucagon family.
Database links:
Entrez Gene: 2695 Human
Omim: 137240 Human
SwissProt: P09681 Human
Unigene: 1454 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
胃泌素抑制肽（GIP）是胃腸道的一種由42個(gè)氨基酸組成的多肽激素，又稱為葡萄糖依賴性促胰島素多肽（glucose-dependent insulinotropic peptide，GIP）他強(qiáng)烈抑制胃分泌和運(yùn)動(dòng)，也可調(diào)節(jié)胰島素的釋放。GIP屬于Glucagon家族成員。
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