| 產(chǎn)品編號(hào) |
bs-2800R-BF555 |
| 英文名稱(chēng) |
Rabbit Anti-Endo G/BF555 Conjugated antibody
|
| 中文名稱(chēng) |
BF555標(biāo)記的核酸內(nèi)切酶G抗體 |
| 別 名 |
EndoG; Endonuclease G; Endonuclease G mitochondrial; EndonucleaseG; FLJ27463; ENDOG; NUCG_HUMAN; Endo G. |
| 規(guī)格價(jià)格 |
100ul/2980元
購(gòu)買(mǎi) 大包裝/詢(xún)價(jià) |
| 說(shuō) 明 書(shū) |
100ul
|
| 研究領(lǐng)域 |
腫瘤 細(xì)胞生物 免疫學(xué) 染色質(zhì)和核信號(hào) 線(xiàn)粒體 |
| 抗體來(lái)源 |
Rabbit |
| 克隆類(lèi)型 |
Polyclonal |
| 交叉反應(yīng) |
Mouse, Rat,
(predicted: Human, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
|
| 產(chǎn)品應(yīng)用 |
IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 |
35kDa |
| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
1mg/ml |
| 免 疫 原 |
KLH conjugated synthetic peptide derived from human Endo G |
| 亞 型 |
IgG |
| 純化方法 |
affinity purified by Protein A |
| 儲(chǔ) 存 液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background:
The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA. [provided by RefSeq, Jul 2008].
Function:
Cleaves DNA at double-stranded (DG)n.(DC)n and at single-stranded (DC)n tracts. In addition to deoxyribonuclease activities, also has ribonuclease (RNase) and RNase H activities. Capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
Subunit:
Homodimer.
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the DNA/RNA non-specific endonuclease family.
Database links:
Entrez Gene: 2021 Human
Entrez Gene: 13804 Mouse
Entrez Gene: 362100 Rat
Omim: 600440 Human
SwissProt: Q14249 Human
SwissProt: O08600 Mouse
Unigene: 224137 Human
Unigene: 474473 Mouse
Unigene: 3807 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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