| 產(chǎn)品編號(hào) | bs-0357R-BF488 |
| 英文名稱 | Rabbit Anti-TRH/BF488 Conjugated antibody |
| 中文名稱 | BF488標(biāo)記的促甲狀腺素釋放激素抗體 |
| 別 名 | Thyrotropin releasing hormone; Protirelin; Thyroliberin [Precursor]; Thyroliberin; Thyrotropin releasing factor; TRF; TRH; TRH_HUMAN; TSH releasing factor. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 神經(jīng)生物學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 生長(zhǎng)因子和激素 內(nèi)分泌病 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Rat, (predicted: Human, Mouse, Chicken, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated TRH (pGlu-His-Pro-Amide) |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]. （L-Pyroglutamyl-L-histidyl-L-prolinamide）pGlu-His-Pro Amide, C18H26N6O6 Function: Thyrotropin releasing hormone (TRH) is a tripeptide hormone that stimulates the release of thyroid stimulating hormone and prolactin by the anterior pituitary. TRH is produced by the hypothalamus and travels across the median eminence to the pituitary via the hypophyseal portal system. In addition to the brain, TRH can also be detected in other areas of the body including the gastrointestinal system and pancreatic islets. Subcellular Location: Secreted Tissue Specificity: Hypothalamus. Expressed in the hair follicle epithelium (at protein level). Similarity: Belongs to the TRH family. Database links: Entrez Gene: 7200 Human Entrez Gene: 22044 Mouse Omim: 275120 Human SwissProt: P20396 Human SwissProt: Q62361 Mouse Unigene: 1363 Mouse Unigene: 22 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 促甲狀腺激素釋放激素(TRH)是下丘腦合成及分泌的一種下丘腦激素，它可以促進(jìn)垂體促甲狀腺激素的合成與分泌。促甲狀腺激素釋放激素的合成及分泌可以受血液中甲狀腺激素的調(diào)節(jié)。血液中甲狀腺激素增高(甲亢)可以抑制下丘腦促甲狀腺激素釋放激素(TRH)的生成，繼而使垂體促甲狀腺激素生成減少，甲狀腺激素增高也可以直接抑制垂體促甲狀腺激素的生成。血液中甲狀腺激素減少(甲低)可以興奮下丘腦促甲狀腺激素釋放激素(TRH)，繼而引起垂體促甲狀腺激素生成增加，甲狀腺激素減少還可以直接興奮垂體促甲狀腺激素的生成。 |
