| 產(chǎn)品編號 | IHC0469H |
| 英文名稱 | Human TNFAIP3 Ready-To-Use IHC Kit |
| 中文名稱 | 人腫瘤壞死因子α誘導(dǎo)蛋白3即用型免疫組化試劑盒 |
| 別 名 | Tnfip3; A20; AISBL; OTUD7C; TNFA1P2; AISBL; MGC104522; MGC138687; MGC138688; OTU domain containing protein 7C; OTU domain-containing protein 7C; OTUD7C; Putative DNA binding protein A20; Putative DNA-binding protein A20; TNAP3_HUMAN; TNF alpha-induced protein 3; TNFA1P2; TNFAIP 3; TNFAIP3 (A20); TNFAIP3; Tumor necrosis factor alpha induced protein 3; Tumor necrosis factor alpha-induced protein 3; Tumor necrosis factor induced protein 3; Tumor necrosis factor inducible protein A20; tumor necrosis factor; alpha-induced protein 3; Zinc finger protein A20; Tumor necrosis factor alpha-induced protein 3 |
| 克 隆 號 | |
| 適用樣品基質(zhì) | FFPE tissue |
| 保存條件 | Please store components at the temperatures indicated on the individual tube labels. The kit is stable for 6 months from the date of receipt. |
| 產(chǎn)品介紹 |
TNFAIP3, also known as A20, is located in chromosome band 6q23, a region that is often deleted in B cell lymphomas. Recently, it was identified as a tumor suppressor gene in Hodgkin lymphoma and several subtypes of non-Hodgkin lymphomas. TNFAIP3 was initially identified as a zinc-finger protein that is rapidly and transiently induced by TNF-a, inhibiting NF-kappa-B-dependent gene expression, and protecting cells from TNF-a-cytotoxicity. Overexpression of TNFAIP3 also inhibits the TLR2- and TLR4-mediated interleukin-8 synthesis in airway epithelial cells, suggesting that TNFAIP3 also acts as a negative regulator of TLR-mediated inflammatory responses, thereby protecting the host against harmful over-responses to pathogens. At least two isoforms of TNFAIP3 are known to exist. SWISS: P21580 Gene ID: 7128 |
| 產(chǎn)品圖片 |
Immunohistochemical analysis of paraffin embedded human placenta tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
Immunohistochemical analysis of paraffin embedded human kidney tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
Immunohistochemical analysis of paraffin embedded human hepatocellular carcinoma tissue slide using IHC0469H (Human TNFAIP3 IHC Kit).
|
