產(chǎn)品編號(hào) | bsm-30297M |
英文名稱(chēng) | Rat CD8a Mouse mAb |
中文名稱(chēng) | 大鼠CD8a單克隆抗體 |
別 名 | CD8 antigen, alpha polypeptide(p32); CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; CD8A_HUMAN; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen. |
抗體來(lái)源 | Mouse |
克隆類(lèi)型 | Monoclonal |
克 隆 號(hào) | 2C5 |
交叉反應(yīng) | (predicted: Rat) |
產(chǎn)品應(yīng)用 | Flow-Cyt=1:50-100
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 27 kDa |
檢測(cè)分子量 | 32 |
性 狀 | Liquid |
亞 型 | Mouse IgG1, k |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 0.01M TBS (pH7.4). |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
CD8 (cluster of differentiation 8) is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. There are two isoforms of the protein, alpha and beta, each encoded by a different gene. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells.The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides. |