產(chǎn)品編號(hào) | bsm-30285A |
英文名稱(chēng) | mouse LPAM-1 Rat mAb |
中文名稱(chēng) | 小鼠LPAM-1單克隆抗體 |
別 名 | Integrin α4β7; α4β7 Integrin, CD49d/β7, LPAM-1, ITGA4, ITGB7; |
抗體來(lái)源 | Rat |
克隆類(lèi)型 | Monoclonal |
克 隆 號(hào) | 6D4 |
交叉反應(yīng) | (predicted: Mouse) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | kDa |
檢測(cè)分子量 | |
性 狀 | Liquid |
亞 型 | |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 0.01M TBS (pH7.4). |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues. |