產(chǎn)品編號 | bsm-30222M |
英文名稱 | human CD366 Mouse mAb |
中文名稱 | 人CD366/PE單克隆抗體 |
別 名 | TIM-3; Tim 3; TIM3; TIMD-3; TIMD3; HAVR2_HUMAN; Hepatitis A virus cellular receptor 2; HAVcr-2; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; CD366; |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
克 隆 號 | 5B2 |
交叉反應(yīng) | (predicted: Human) |
產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 31 kDa |
檢測分子量 | 40 |
性 狀 | Liquid |
亞 型 | Mouse IgG1, k |
純化方法 | affinity purified by Protein G |
緩 沖 液 | 0.01M TBS (pH7.4). |
保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011] |