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NUCB2 Rabbit pAb (bs-23044R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
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產品編號 bs-23044R
英文名稱 NUCB2 Rabbit pAb
中文名稱 新的飽食分子蛋白抗體
別    名 NUCB2_HUMAN; Nucleobindin-2; DNA-binding protein NEFA; Epididymis secretory protein Li 109; Gastric cancer antigen Zg4; Prepronesfatin; Nesfatin-1; NEFA; nucleobindin 2; HEL-S-109;  
研究領域 心血管  細胞生物  免疫學  神經生物學  生長因子和激素  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Human,Rabbit,Sheep,Cow,Chicken,Dog,Horse)
產品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 50 kDa
檢測分子量
細胞定位 細胞核 細胞漿 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Nucleobindin 2: 251-350/420 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains. [provided by RefSeq, Oct 2011].

Function:
Calcium-binding protein. May have a role in calcium homeostasis.
Nesfatin-1: Anorexigenic peptide, seems to play an important role in hypothalamic pathways regulating food intake and energy homeostasis, acting in a leptin-independent manner. May also exert hypertensive roles and modulate blood pressure through directly acting on peripheral arterial resistance.

Subcellular Location:
Golgi apparatus. Membrane; Peripheral membrane protein. Cytoplasm. Secreted. Endoplasmic reticulum. Nucleus envelope. Note=Golgi retention is mediated by its N-terminal region.
Nesfatin-1: Secreted.

Tissue Specificity:
Predominantly expressed in spleen, testis and normal stomach.

Similarity:
Belongs to the nucleobindin family.
Contains 2 EF-hand domains.

SWISS:
P80303

Gene ID:
4925

Database links:

Entrez Gene: 4925 Human

Entrez Gene: 53322 Mouse

Entrez Gene: 59295 Rat

Omim: 608020 Human

SwissProt: P80303 Human

SwissProt: P81117 Mouse

SwissProt: Q9JI85 Rat

Unigene: 654599 Human

Unigene: 9901 Mouse

Unigene: 41602 Rat



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