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ACTR1B Rabbit pAb (bs-19902R)  
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產(chǎn)品編號 bs-19902R
英文名稱 ACTR1B Rabbit pAb
中文名稱 肌動蛋白相關蛋白1B抗體
別    名 Actin related protein 1B; Actin-related protein 1B; ACTR 1B; ACTY_HUMAN; ARP 1B; ARP1 actin related protein 1 homolog B; ARP1 actin related protein 1 homolog B centractin beta(yeast); ARP1 actin related protein 1 homolog B centractin beta; ARP1 actin related protein 1 yeast homolog B centractin beta; ARP1 yeast homolog B; ARP1B; beta centractin; beta-centractin; Centractin beta(Yeast); Centractin beta; CTRN 2; CTRN2; PC 3; PC3.  
研究領域 細胞生物  信號轉(zhuǎn)導  結合蛋白  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human (predicted: Mouse,Rabbit,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ARP1B: 301-376/376 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein and is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins, which are of equal length and share 90% amino acid identity, are present in a constant ratio of approximately 1:15 in the dynactin complex. [provided by RefSeq, Aug 2008]

Function:
Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome.

Subcellular Location:
Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome.

Similarity:
Belongs to the actin family. ARP1 subfamily.

SWISS:
P42025

Gene ID:
10120

Database links:

Entrez Gene: 100125305 Cow

Entrez Gene: 611680 Dog

Entrez Gene: 10120 Human

Entrez Gene: 226977 Mouse

Entrez Gene: 316333 Rat

Omim: 605144 Human

SwissProt: A4IFE3 Cow

SwissProt: P42025 Human

SwissProt: Q8R5C5 Mouse

Unigene: 98791 Human

Unigene: 28521 Mouse



產(chǎn)品圖片
Sample: Molt-4(Human) Cell Lysate at 30 ug HepG2(Human) Cell Lysate at 30 ug Primary: Anti-PC3 (bs-19902R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 42 kD Observed band size: 42 kD
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