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PIP5K2B Rabbit pAb (bs-18538R)  
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產(chǎn)品編號 bs-18538R
英文名稱 PIP5K2B Rabbit pAb
中文名稱 磷脂酰肌醇-5-磷酸鹽-4激酶2型β抗體
別    名 PIP5K2 beta; phosphatidylinositol 5-phosphate 4-kinase type-2 beta; phosphatidylinositol 5-phosphate 4-kinase type-2; 1 phosphatidylinositol 4 phosphate 5 kinase 2 beta; 1 phosphatidylinositol 4 phosphate kinase; 1-phosphatidylinositol-5-phosphate 4-kinase 2-beta; Diphosphoinositide kinase 2 beta; Diphosphoinositide kinase 2-beta; diphosphoinositide kinase; EC 2.7.1.68; Phosphatidylinositol 4 phosphate 5 kinase type II beta; phosphatidylinositol 4 phosphate 5 kinase type II beta isoform a; Phosphatidylinositol-5-phosphate 4-kinase type II beta; Phosphatidylinositol-5-phosphate 4-kinase type-2 beta; PI(5)P 4-kinase type II beta; PI42B_HUMAN; PI5P4KB; Pip4k2b; PIP4KII-beta; PIP5K2B; PIP5KII beta; PIP5KIIB; PIP5KIIbeta; PTDINS(4) P 5 kinase; PtdIns(4) P 5-kinase isoform 2 beta; PtdIns(5)P-4-kinase isoform 2-beta.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  細(xì)胞膜蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human (predicted: Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog,Horse,Xenopus laevis)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 47 kDa
檢測分子量
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PIP5K2B: 101-200/416 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]

Function:
Participates in the biosynthesis of phosphatidylinositol-4,5-bisphosphate.

Subcellular Location:
Endoplasmic reticulum membrane. Cell membrane. Associated with the plasma membrane and the endoplasmic reticulum.

Tissue Specificity:
Highly expressed in brain, heart, pancreas, skeletal muscle and kidney. Detected at lower levels in placenta, lung and liver.

Similarity:
Contains 1 PIPK domain.

SWISS:
P78356

Gene ID:
8396

Database links:

Entrez Gene: 539211 Cow

Entrez Gene: 8396 Human

Entrez Gene: 108083 Mouse

Entrez Gene: 89812 Rat

Entrez Gene: 399394 Xenopus laevis

Omim: 603261 Human

SwissProt: P78356 Human

SwissProt: Q80XI4 Mouse

SwissProt: O88377 Rat

Unigene: 260603 Human

Unigene: 39700 Mouse

Unigene: 30025 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Human cervical cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PIP5K2B) Polyclonal Antibody, Unconjugated (bs-18538R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
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