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JAM2 Rabbit pAb (bs-17213R)  
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產品編號 bs-17213R
英文名稱 JAM2 Rabbit pAb
中文名稱 連接粘附分子2抗體
別    名 Junctional Adhesion Molecule 2; C21orf43; CD 322; CD322; CD322 antigen; JAM 2; JAM B; JAM IT/VE JAM; JAM, vascular endothelial; JAM-2; JAM-B; JAM2; JAM2_HUMAN; JAMB; Jcam2; Junction adhesion molecule 2; Junction adhesion molecule B; Junctional adhesion molecule 2; Junctional adhesion molecule B; PRO 245; PRO245; Vascular endothelial junction associated molecule; Vascular endothelial junction-associated molecule; VE JAM; VE-JAM; VEJAM.  
研究領域 細胞生物  免疫學  發(fā)育生物學  信號轉導  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse,Rat (predicted: Rabbit,Cow,Chimpanzee, Macaque Monkey,Gorilla, Orangutan)
產品應用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 48 kDa
檢測分子量
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human JAM2: 201-298/298 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]

Function:
May play a role in the processes of lymphocyte homing to secondary lymphoid organs.

Subcellular Location:
Cell junction > tight junction. Cell membrane. Localized at tight junctions of both epithelial and endothelial cells.

Tissue Specificity:
Highest expression in the heart, placenta, lung, foreskin and lymph node. Prominently expressed on high endothelial venules, also present on the endothelia of other vessels. Localized to the intercellular boundaries of high endothelial cells.

Similarity:
Belongs to the immunoglobulin superfamily.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.

SWISS:
P57087

Gene ID:
58494

Database links:

Entrez Gene: 538846 Cow

Entrez Gene: 58494 Human

Entrez Gene: 67374 Mouse

Entrez Gene: 619374 Rat

Omim: 606870 Human

SwissProt: P57087 Human

SwissProt: Q9JI59 Mouse

Unigene: 517227 Human

Unigene: 41758 Mouse

Unigene: 6473 Rat



產品圖片
Sample: Heart (Mouse) Lysate at 40 ug Primary: Anti-JAM2 (bs-17213R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48kD Observed band size: 50kD
Sample: H9C2 Cell (Rat) Lysate at 30 ug Primary: Anti-JAM2 (bs-17213R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 48kD Observed band size: 50kD
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