| 產(chǎn)品編號(hào) | bs-9710R |
| 英文名稱(chēng) | NOP2 Rabbit pAb |
| 中文名稱(chēng) | 增殖相關(guān)核仁抗原抗體 |
| 別 名 | Proliferation Associated Nucleolar Antigen: NOL 1; NUCLEOLAR ANTIGEN p120; NOP2_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 細(xì)胞周期蛋白 細(xì)胞分化 表觀(guān)遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Rat (predicted: Human,Mouse,Rabbit,Sheep,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 89 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human NOL1: 1-100/812 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Proliferation-associated nucleolar antigen is expressed in mid G1 phase with peak level during the S phase and a rapid degradation during late mitosis. Its expression in breast carcinoma is correlated with patient prognosis. Function: May play a role in the regulation of the cell cycle andthe increased nucleolar activity that is associated with the cellproliferation. May act as ribosomal RNA methyltransferase. Subunit: Interaction with MCRS1. Subcellular Location: Nuclear Similarity: Belongs to the methyltransferase superfamily. RsmB/NOPfamily. SWISS: P46087 Gene ID: 4839 Database links: Entrez Gene: 4839 Human Entrez Gene: 110109 Mouse Omim: 164031 Human SwissProt: P46087 Human SwissProt: Q922K7 Mouse Unigene: 534334 Human Unigene: 29203 Mouse Unigene: 32804 Rat |
| 產(chǎn)品圖片 |
Paraformaldehyde-fixed, paraffin embedded (rat testis tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (NOP2) Polyclonal Antibody, Unconjugated (bs-9710R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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