| 產(chǎn)品編號 | bs-8298R |
| 英文名稱 | UQCRC1 Rabbit pAb |
| 中文名稱 | 輔酶細胞色素C還原酶核心蛋白1抗體 |
| 別 名 | Ubiquinol-Cytochrome C Reductase Core Protein I; mitochondrial; Complex III subunit 1; Core protein I; Cytochrome b c1 complex subunit 1, mitochondrial; Cytochrome b-c1 complex subunit 1; D3S3191; OTTHUMP00000164820; QCR1; QCR1_HUMAN; Ubiquinol cytochrome |
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Specific References (1) | bs-8298R has been referenced in 1 publications.
[IF=4] Huang Bangliang. et al. PSA controls hepatic lipid metabolism by regulating the NRF2 signaling pathway. J Mol Cell Biol. 2021 May;: WB ; Human.
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| 研究領(lǐng)域 | 細胞生物 信號轉(zhuǎn)導(dǎo) 線粒體 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human (predicted: Mouse,Rat,Cow,Monkey,y) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 49 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞漿 細胞膜 線粒體 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human UQCRC1: 65-170/480 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Function: This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Subunit: The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1). Subcellular Location: Mitochondrion inner membrane. Post-translational modifications: Acetylation of Lys-138 is observed in liver mitochondria from fasted mice but not from fed mice. Similarity: Belongs to the peptidase M16 family. UQCRC1/QCR1 subfamily. SWISS: Q6V1X1 Gene ID: 54878 Database links: Entrez Gene: 54878 Human Entrez Gene: 74388 Mouse Omim: 606819 Human SwissProt: Q6V1X1 Human SwissProt: Q80YA7 Mouse Unigene: 591106 Human Unigene: 202749 Mouse Unigene: 391842 Mouse |
| 產(chǎn)品圖片 |
Tissue/cell: human lung carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-UQCRC1 Polyclonal Antibody, Unconjugated(bs-8298R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
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