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TFDP3 Rabbit pAb (bs-6400R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-6400R
英文名稱 TFDP3 Rabbit pAb
中文名稱 轉錄因子DP3/肝癌相關抗原661抗體
別    名 Cancer/testis antigen 30; CT30; E2F-like; HCA661; Hepatocellular carcinoma-associated antigen 661; TFDP3; Transcription factor Dp family member 3; TFDP3_HUMAN.  
研究領域 細胞生物  細胞周期蛋白  轉錄調(diào)節(jié)因子  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Rabbit,Cow,Chicken,Dog,Horse)
產(chǎn)品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 45 kDa
檢測分子量
細胞定位 細胞核 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TFDP3: 301-405/405 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.

Function:
Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.

Subunit:
Heterodimer: with E2F family members. TFDP3/E2F heterodimers do not bind DNA and repress E2F-dependent transcriptional activity.

Subcellular Location:
Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.

Tissue Specificity:
Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.

Similarity:
Belongs to the E2F/DP family.

SWISS:
Q5H9I0

Gene ID:
51270

Database links:

Entrez Gene: 51270 Human

SwissProt: Q5H9I0 Human

Unigene: 142908 Human



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