| 產(chǎn)品編號 | bs-6080R |
| 英文名稱 | XAB2 Rabbit pAb |
| 中文名稱 | XAB2蛋白抗體 |
| 別 名 | 0610041O14Rik; adapter protein ATH 55; Adapter protein ATH-55; Ath55; AV025587; Crn related protein kim1; crn-related protein kim1; DKFZp762C1015; HCNP; HCNP protein; HCRN; KIAA1177; NTC90; PP3898; Pre-mRNA-splicing factor SYF1; Protein HCNP; RNA splicing |
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Specific References (1) | bs-6080R has been referenced in 1 publications.
[IF=4.966] Shuiming Guo. et al. Pre‐ischemic renal lavage protects against renal ischemia‐reperfusion injury by attenuation of local and systemic inflammatory responses. Faseb J. 2020 Dec;34(12):16307-16318 WB ; Rat.
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| 研究領域 | 腫瘤 細胞生物 免疫學 染色質和核信號 表觀遺傳學 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | (predicted: Human,Mouse,Rat,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 100 kDa |
| 檢測分子量 | |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PBP/HCNP: 65-160/855 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 antibodies resulted in the inhibition of both transcription coupled repair and transcription. Function: Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing. Subunit: Associates with RNA polymerase II, the TCR-specific proteins CKN1/CSA and ERCC6/CSB, and XPA. Identified in the spliceosome C complex. Subcellular Location: Nucleus (By similarity). Note=Detected in the splicing complex carrying pre-mRNA (By similarity). Similarity: Belongs to the crooked-neck family. Contains 14 HAT repeats. SWISS: Q9HCS7 Gene ID: 56949 Database links: Entrez Gene: 56949 Human Entrez Gene: 67439 Mouse Omim: 610850 Human SwissProt: Q9HCS7 Human SwissProt: Q9DCD2 Mouse Unigene: 9822 Human Unigene: 23739 Mouse Unigene: 24921 Rat |
| 1、抗體溶解方法 | |
| 2、抗體修復方式 | |
| 3、常用試劑的配制 | |
| 4、免疫組化操作步驟 | |
| 5、免疫組化問題解答 | |
| 6、Western Blotting 操作步驟 | |
| 7、Western Blotting 問題解答 | |
| 8、關于肽鏈的設計 | |
| 9、多肽的溶解與保存 | |
| 10、酶標抗體效價測定程序 | |
