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CPT1B Rabbit pAb (bs-5045R)  
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產(chǎn)品編號(hào) bs-5045R
英文名稱 CPT1B Rabbit pAb
中文名稱 肉毒堿棕櫚酰基轉(zhuǎn)移酶1B抗體
別    名 muscle isoform; Carnitine O palmitoyltransferase I mitochondrial muscle isoform; Carnitine O palmitoyltransferase I muscle isoform; Carnitine O-palmitoyltransferase 1, muscle isoform; Carnitine O-palmitoyltransferase I; Carnitine palmitoyltransferase 1A(m  
Specific References  (2)     |     bs-5045R has been referenced in 2 publications.
[IF=4.91] Huebbe, Patricia, et al. "Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization–studies in gene targeted replacement mice." Molecular Nutrition & Food Research (2014).  WB ;  Mouse.  
[IF=3.06] Yuan J et al. L-Carnitine Is Involved in Hyperbaric Oxygen-Mediated Therapeutic Effects in High Fat Diet-Induced Lipid Metabolism Dysfunction. Molecules. 2020 Jan 1;25(1). pii: E176.  WB ;  Mouse.  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  轉(zhuǎn)錄調(diào)節(jié)因子  線粒體  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,Rat (predicted: Mouse,Pig,Sheep,Cow,Dog,Horse)
產(chǎn)品應(yīng)用 Flow-Cyt=3ug/Test
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 85 kDa
檢測(cè)分子量
細(xì)胞定位 細(xì)胞漿 線粒體
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CPT1B: 501-600/772 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].

Function:
Strong expression in heart and skeletal muscle. No expression in liver and kidney.

Subcellular Location:
Mitochondrion outer membrane.

Similarity:
Belongs to the carnitine/choline acetyltransferase family.

SWISS:
Q92523

Gene ID:
1375

Database links:

Entrez Gene: 1375 Human

Entrez Gene: 12895 Mouse

Omim: 601987 Human

SwissProt: Q92523 Human

SwissProt: Q924X2 Mouse

SwissProt: Q8HY46 Pig

Unigene: 439777 Human

Unigene: 609867 Human

Unigene: 227738 Mouse

Unigene: 112195 Human

Unigene: 231465 Mouse

Unigene: 43113 Rat



產(chǎn)品圖片
Blank control: Hela. Primary Antibody (green line): Rabbit Anti-CPT1B antibody (bs-5045R) Dilution: 3μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Secondary Antibody: Goat anti-rabbit IgG-AF647 Dilution: 3μg /test. Protocol The cells were incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. The secondary antibody used for 40 min at room temperature. Acquisition of 20,000 events was performed.
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