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DPPA2 Rabbit pAb (bs-0597R)  
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50ul/1180.00元
100ul/1980.00元
200ul/2800.00元
大包裝/詢價
產(chǎn)品編號 bs-0597R
英文名稱 DPPA2 Rabbit pAb
中文名稱 多能發(fā)育相關(guān)基因2抗體
別    名 Developmental Pluripotency Associated 2; developmental pluripotency associated gene2; PESCRG1; Pluripotent embryonic stem cell related protein 1; cancer/testis antigen 100; CT100; developmental pluripotency-associated gene 2; developmental pluripotency-associated protein 2; ECAT15-2; embryonic stem cell(ESC) associated transcript 15-2; PESCRG1; Pluripotent embryonic stem cell related protein 1; Pluripotent embryonic stem cell-related gene 1; Pluripotent embryonic stem cell-related gene 1 protein .  
研究領(lǐng)域 細胞生物  免疫學  發(fā)育生物學  神經(jīng)生物學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 (predicted: Human,Mouse,Rat)
產(chǎn)品應用 ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 34 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human DPPA2: 211-301/301 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 SCRG1 (scrapie-responsive protein 1) is a 98 amino acid secreted protein that belongs to the SCRG1 family. The SCRG1 protein contains a 20-amino acid signal peptide, and is expressed abundantly in the central nervous system of human adult, but not at all in fetal brain. The protein is targeted to the Golgi apparatus and large dense-core vesicles/secretory granules in neurons. High levels of SCRG1 transcripts are also observed in testis and aorta. SCRG1 is associated with neurodegenerative changes observed in transmissible spongiform encephalopathies. It may play a role in host response to prion-associated infections. The SCRG1 protein may be partly included in the membrane or secreted by the cells due to its hydrophobic N-terminus. The human and mouse SCRG1 proteins share 83% sequence identity. The SCRG1 gene is conserved in chimpanzee, cow, mouse, rat and chicken, and maps to human chromosome 4q34.1.

Function:
Dppa2 is a SAP domain protein expressed only in pluripotent cells and the developing germ line.

Subcellular Location:
Secreted.

Tissue Specificity:
Expressed abundantly in the central nervous system of adult, but not at all in fetal brain. High levels of SCRG1 transcripts are also observed in testis and aorta.

Similarity:
Belongs to the SCRG1 family.

SWISS:
Q7Z7J5

Gene ID:
151871

Database links:

Entrez Gene: 151871 Human

Entrez Gene: 73703 Mouse

Omim: 614445 Human

SwissProt: Q7Z7J5 Human

SwissProt: Q9CWH0 Mouse

Unigene: 351113 Human

Unigene: 27857 Mouse



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